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ABSTRACTDuring the outbreak of Covid-19, the policy of working from home for employees and studying from Neuromuscular disease in childhood result in dysfunction of chest wall and lung movement that interfere ventilation function and gas exchange. Without vital respiratory pump, ventilation, gas exchange function and cough ability would be compromised and could result in complications such as pneumonia, atelectasis, and respiratory failure. Comorbid factors in cardiovascular, musculoskeletal, nutrition, and gastrointestinal could aggravate respiratory morbidity and mortality if not adequately treated. This paper was written to review anatomy and physiology of neurorespiratory system, pathophysiology of respiratory complication in neuromuscular disease, clinical assessment and respiratory monitoring of childhood neuromuscular disease from Physical Medicine and Rehabilitation point of view.Keywords: assessment, neuromuscular disease, pediatric, respiratory
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