Fatigue, Sleepiness, Anxiety-Depression Score, Calories And BDNF Serum Level, Quality Of Life Alteration During Holy Ramadhan Month

Main Article Content

Irma Ruslina Defi
Deta Tanuwidjadja
Jennie Jennie


Introduction: Ramadhan fasting increases mental and physical health. The study aims to evaluate the effect of Ramadhan fasting on fatigue, sleepiness, depression and anxiety mood, quality of life (QoL), and Brain-derived neurotrophic factor (BDNF) serum level.
Methods: Twenty participants are included in the fasting group (FG), and nineteen participants are included in the non-fasting group (NFG). Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS), hospital depression and anxiety score (HADS), Beck depression inventory (BDI)-II, Short form 12 (SF-12), and BDNF in both groups were assessed at five-time points: one week before Ramadhan (T1), in the middle of Ramadhan (T2), the last days of Ramadhan (T3), one week after Ramadhan fasting (T4) two weeks after Ramadhan (T5).
Results: We found no significant differences across the time points between FG and NFG groups in all variables (p>0.05). There is a significant correlation between fatigue VAS with BDNF serum levels (r > r table), SF-12 PCS (r>r table) with BDNF, SF-12 MCS (r>r table). There is no correlation between fatigue, depression and anxiety intensity, sleepiness, QoL, BDI-II, and BDNF serum levels with calories, BDI-II, and BDNF of fasting group in Ramadhan (r < r table).
Conclusions: Ramadhan fasting has positive effects on fatigue and mood. Ramadhan fasting does not have a significant effect on sleepiness, physical exercise, and calories consumed. Fatigue VAS and SF-12 PCS can replace the serum BDNF.

Article Details

Original Article
Author Biographies

Irma Ruslina Defi, Medical Staff

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Padjadjaran University, Dr.Hasan Sadikin General Hospital, Bandung, Indonesia

Deta Tanuwidjadja, Medical Staff

Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Padjadjaran University, Dr.Hasan Sadikin General Hospital, Bandung, Indonesia

Jennie Jennie, Medical Staff

Faculty of Medicine, Maranatha Christian University, Bandung, Indonesia


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