The Effect of Static Ergocycle on Cardiorespiratory Endurance in Early Ambulatory Duchenne Muscular Dystrophy Patient: A Case Report
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Published:
Dec 28, 2024
Keywords:
Duchene Muscular Dystrophy, Rehabilitation Management
Main Article Content
Abstract
Duchenne muscular dystrophy (DMD) is a debilitating genetic disorder affecting approximately 1 in 3600-6000 live male births, resulting from mutations in the dystrophin gene. This case report describes a 5-year-old boy in the early ambulatory stage of DMD, presenting with characteristic symptoms such as difficulty to stand, muscle weakness, accidental falls, and impaired motor skills.
The patient underwent a multidisciplinary approach involving medical and rehabilitative interventions to improve quality of life and delay disease progression. The rehabilitation program included physical activities, stretching exercises, and environmental optimization.
The spirometry and 6-Minute Walk Test (6MWT) revealed restrictive lung patterns and reduced exercise capacity. The patient's adherence to corticosteroid treatment, ongoing monitoring, and comprehensive rehabilitation strategies are crucial for maintaining optimal muscle function, and enhancing overall QoL. Pulmonary function evaluation and management are also emphasized, given the common association of pulmonary complications with mortality in DMD.
The patient underwent a multidisciplinary approach involving medical and rehabilitative interventions to improve quality of life and delay disease progression. The rehabilitation program included physical activities, stretching exercises, and environmental optimization.
The spirometry and 6-Minute Walk Test (6MWT) revealed restrictive lung patterns and reduced exercise capacity. The patient's adherence to corticosteroid treatment, ongoing monitoring, and comprehensive rehabilitation strategies are crucial for maintaining optimal muscle function, and enhancing overall QoL. Pulmonary function evaluation and management are also emphasized, given the common association of pulmonary complications with mortality in DMD.
Article Details
How to Cite
Kusuma Wardhani, R., & Lestari, F. (2024). The Effect of Static Ergocycle on Cardiorespiratory Endurance in Early Ambulatory Duchenne Muscular Dystrophy Patient: A Case Report. Indonesian Journal of Physical Medicine and Rehabilitation, 13(2), 129 - 134. https://doi.org/10.36803/indojpmr.v13i2.419
Section
Case Report
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References
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11. Bianchi C, Baiardi P. Cough Peak Flows: Standard Values for Children and Adolescents. Am J Phys Med Rehabil. 2008 Jun;87(6):461–7. Available at: https://pubmed.ncbi.nlm.nih.gov/18496248/. Accessed February 2, 2024.
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2. Bushby K, Finkel R, Birnkrant DJ, Case LE, Clemens PR, Cripe L, et al. Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management. Lancet Neurol. 2010 Jan;9(1):77–93. Available at: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(09)70271-6/fulltext. Accessed February 2, 2024.
3. Venugopal V, Pavlakis S. Duchenne Muscular Dystrophy. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024. Available at: https://www.ncbi.nlm.nih.gov/books/NBK482346/. Accessed February 2, 2024.
4. McDonald C. Neuromuscular Diseases. In: Pediatric Rehabilitation Principles and Practise. 5th ed.
5. Birnkrant DJ, Bushby K, Bann CM, Alman BA, Apkon SD, Blackwell A, et al. Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management. Lancet Neurol. 2018 Apr;17(4):347–61. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889091/. Accessed February 2, 2024.
6. Birnkrant DJ, Bushby K, Bann CM, Apkon SD, Blackwell A, Colvin MK, et al. Diagnosis and management of Duchenne muscular dystrophy, part 3: primary care, emergency management, psychosocial care, and transitions of care across the lifespan. Lancet Neurol. 2018 May;17(5):445–55. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902408/. Accessed February 2, 2024.
7. Case LE, Apkon SD, Eagle M, Gulyas A, Juel L, Matthews D, et al. Rehabilitation Management of the Patient With Duchenne Muscular Dystrophy. Pediatrics. 2018 Oct 1;142(Supplement_2):S17–33. https://publications.aap.org/pediatrics/article-abstract/142/Supplement_2/S17/11565/Rehabilitation-Management-of-the-Patient-With?redirectedFrom=fulltext. Accessed February 2, 2024.
8. Children’s of Alabama. Rehabilitation Standards of Care for Duchenne Muscular Dystrophy. Pediatric Rehabilitation Medicine; Available at: https://www.parentprojectmd.org/wp-content/uploads/2018/06/EDT18_AL_Care_Davis_Rehabilitation.pdf. Accessed February 2, 2024.
9. Lott DJ, Taivassalo T, Cooke KD, Park H, Moslemi Z, Batra A, et al. Safety, feasibility, and efficacy of strengthening exercise in Duchenne Muscular Dystrophy. Muscle Nerve. 2021 Mar;63(3):320–6. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9254904/. Accessed February 2, 2024.
10. Hammer S, Toussaint M, Vollsæter M, Nesbjørg Tvedt M, Drange Røksund O, Reychler G, et al. Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis. J Rehabil Med. 2021 Dec 2. Available at: https://medicaljournalssweden.se/jrm/article/view/985. Accessed February 2, 2024.
11. Bianchi C, Baiardi P. Cough Peak Flows: Standard Values for Children and Adolescents. Am J Phys Med Rehabil. 2008 Jun;87(6):461–7. Available at: https://pubmed.ncbi.nlm.nih.gov/18496248/. Accessed February 2, 2024.
12. Lu YM, Lue YJ. Strength and Functional Measurement for Patients with Muscular Dystrophy. In: Hegde M, editor. Muscular Dystroph. InTech; 2012. Available at: https://www.intechopen.com/chapters/36741. Accessed February 2, 2024.