The Effect of Intradialysis Resistance Training on Quality of Life and Physical Activity of End-Stage Chronic Renal Failure Patients Hemodialysis
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Published:
Jun 17, 2025
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Keywords: Chronic kidney disease, hemodialysis, physical activity, quality of life, resistance training
Main Article Content
Abstract
Introduction: Patients with Chronic Kidney Failure have a decreased ability to excrete metabolic wastes. Metabolic wastes that accumulate in the musculoskeletal system are called uremic myopathy. Uremic myopathy is characterized by an increase in muscle protein catabolism which results in a decrease in contractility and muscle mass which causes the patient to tire easily and triggers sedentary behavior and reduces physical activity and quality of life.
Objective: The purpose of this study was to determine the effect of intradialysis resistance exercise on quality of life and level of physical activity in end-stage chronic kidney disease patients undergoing hemodialysis 2 times per week.
Methods: Thirty-nine subjects receive low-intensity resistance exercise for 2 sets of 15 repetitions. Progression of exercise is done by increasing the volume of exercise. Exercises are carried out twice a week for 24 training sessions under the supervision in the hospital. The examination was carried out before and after 24 training sessions including filling out the KDQOL (Kidney Disease and Quality of Life) and IPAQ (International Physical Activity Questionnaire) questionnaires. Statistical analysis using t-test and sign-test
Results: The results showed significant changes in all the variables studied, KDQOL score (p=0.00) and the level of physical activity (p=0.00). The average KDQOL scores before and after exercise were 166.67 and 243.16. Twenty-five research subjects has increased in physical activity level, and fourteen research subjects did not increase in physical activity level
Conclusion: Intradialysis resistance exercise improves quality of life and physical activity level of end-stage chronic kidney disease patients undergoing hemodialysis 2 times per week
Keywords: Chronic kidney disease, hemodialysis, physical activity, quality of life, resistance training
Article Details
How to Cite
Septiani, W., Prabowo, T., Goesasi, R. Z., Darmawan, M. L., & Salamah, H. D. (2025). The Effect of Intradialysis Resistance Training on Quality of Life and Physical Activity of End-Stage Chronic Renal Failure Patients Hemodialysis. Indonesian Journal of Physical Medicine and Rehabilitation, 14(1), 39 - 47. https://doi.org/10.36803/indojpmr.v14i1.424
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Original Article
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16. Bennett PN, Hussein WF, Matthews K, West M, Smith E, Reiterman M, et al. An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study. Kidney Med. 2020 May;2(3):267–75.
2. Taryana AA, Krishnasamy R, Bohm C, Palmer SC, Wiebe N, Boudville N, et al. Physical activity for people with chronic kidney disease: An international survey of nephrologist practice patterns and research priorities. BMJ Open. 2019 Dec 18;9(12).
3. PuJ,JiangZ,WuW,LiL,ZhangL, Li Y, et al. Efficacy and safety of intradialytic exercise in haemodialysis patients: a systematic review and meta-analysis. BMJ Open [Internet]. 2019 Jan 1 [cited 2024 Jul 25];9(1):e020633. Available from: https://bmjopen.bmj.com/content/9/1/ e020633
4. 10 th Report Of Indonesian Renal Registry 2017.
5. 11 th Report Of Indonesian Renal Registry 2018.
6. Kaltsatou A, Sakkas GK, Poulianiti KP, Koutedakis Y, Tepetes K,
Christodoulidis G, et al. Uremic myopathy: is oxidative stress implicated in muscle dysfunction in uremia? Front Physiol [Internet]. 2015 [cited 2024 Jul 25];6(MAR):102. Available from: /pmc/articles/PMC4378187/
7. Therapeutic Exercise: Foundations and Techniques - F.A. Davis Company [Internet]. [cited 2024 Jul 25]. Available from: https://www.fadavis.com/product/phy sical-therapy-therapeutic-exercise- foundations-techniques-kisner-7
8. Kim JC, Shapiro BB, Zhang M, Li Y, Porszasz J, Bross R, et al. Daily physical activity and physical function in adult maintenance hemodialysis patients. J Cachexia Sarcopenia Muscle. 2014 Sep 29;5(3):209–20.
9. Wong SW, Chan YM, Lim TS. Correlates of physical activity level among hemodialysis patients in Selangor, Malaysia. Malays J Nutr. 2011 Dec;17(3):277–86.
10. Song WJ, Sohng KY. Effects of Progressive Resistance Training on Body Composition, Physical Fitness and Quality of Life of Patients on Hemodialysis. J Korean Acad Nurs. 2012;42(7):947.
11. Martins do Valle F, Valle Pinheiro B, Almeida Barros AA, Ferreira Mendonça W, de Oliveira AC, de Oliveira Werneck G, et al. Effects of intradialytic resistance training on physical activity in daily life, muscle strength, physical capacity and quality of life in hemodialysis patients: a randomized clinical trial. Disabil Rehabil [Internet]. 2020 Dec 3 [cited 2024 Jul 26];42(25):3638–44. Available from: https://www.tandfonline.com/doi/abs/ 10.1080/09638288.2019.1606857
12. DeOreo PB. Hemodialysis patient- assessed functional health status predicts continued survival, hospitalization, and dialysis- attendance compliance. American Journal of Kidney Diseases. 1997 Aug;30(2):204–12.
13. Arazi H, Dadvand SS. Effects of circuit-type resistance training on industrial opiate induced neurotransmitter disruption and performance changes of previously addicted men. Biomed Hum Kinet. 2020 Jan 1;12(1):173–81.
14. Chen JLT, Godfrey S, Ng TT, Moorthi R, Liangos O, Ruthazer R, et al. Effect of intra-dialytic, low- intensity strength training on functional capacity in adult haemodialysis patients: a randomized
pilot trial. Nephrology Dialysis Transplantation [Internet]. 2010 Jun 1 [cited 2024 Jul 26];25(6):1936–43. Available from: https://dx.doi.org/10.1093/ndt/gfp739
15. Araújo Filho JC de, Amorim CT de, Brito ACN de L, Oliveira DS de, Lemos A, Marinho PÉ de M. Nível de atividade física de pacientes em hemodiálise: um estudo de corte transversal. Fisioterapia e Pesquisa. 2016 Sep;23(3):234–40.
16. Bennett PN, Hussein WF, Matthews K, West M, Smith E, Reiterman M, et al. An Exercise Program for Peritoneal Dialysis Patients in the United States: A Feasibility Study. Kidney Med. 2020 May;2(3):267–75.